During his 31 years at the College of Pharmacists of Manitoba (formerly the Manitoba Pharmaceutical Association), where he was Registrar from 1999 until his retirement in 2016, Ron Guse helped steer the profession of pharmacy through significant periods of change. He helped develop and champion the new Pharmaceutical Act, passed into law in 2006 and considered the most progressive legislation for pharmacists’ scope of practice at the time. In 2002, working with the regulatory bodies for physicians and nurses, Ron was instrumental in launching Continued Care Prescriptions, which came to serve as a model for collaborative practice agreements in other provinces. And in 1999 he forged ahead through controversy and uncharted territory to establish regulatory guidelines and standards of practice for the new sector of international prescription service pharmacies (also known as cross-border mail order pharmacies).